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Theme 1
Theme I: Prion Ecology - Introduction
Theme I: Prion Ecology - 1. Immunoprophylaxis and Therapy of Bovine Spongiform Encephalopathy
Theme I: Prion Ecology - 2. Development of Models of CWD Transmission and Risk at Multiple Spatial Scales
Theme I: Prion Ecology - 3. Development of Value-Added Applications Derived from Rendering By-product Streams, including Specified Risk Materials
Theme II
Theme II: Prion Biology - Introduction
Theme II: Prion Biology - 1. Using Metabolomics and Proteomics to Identify Novel Biomarkers for Preclinical Diagnosis and Monitoring of Prion Diseases
Theme II: Prion Biology - 2. Peptide and Gene Therapy for Prion Infection
Theme II: Prion Biology - 3. Identification of MiRNA Driven Regulatory Circuits Involved in Prion-Induced Neurodegeneration
Theme II: Prion Biology - 4. Evolutionary Analysis and Structural Modelling of Prion Proteins and Prion Protein-like Molecules
Theme II: Prion Biology - 5. Pathobiology of Prion Protein Aggregates: Mechanism of Toxicity and Propagation of Aggregates Produced in the Cytoplasm
Theme II: Prion Biology - 6. Prion Protein Conversion in Disease: the “Demiglobule” Hypothesis
Theme II: Prion Biology - 7. Molecular Mechanism for Oligomer Formation of Prion Proteins
Theme II: Prion Biology - 8. NMR Studies of Protein Interactions, Conversion Intermediates and Oligomers of PrP
Theme II: Prion Biology - 9. Protein Kinases as Potential Therapeutic Targets in Prion Diseases
Theme II: Prion Biology - 10. Regulation of NMDA Receptors by Prion Proteins
Theme II: Prion Biology - 11. Structural Characterization of Prion Protein-Specific Recombinant Antibodies and Their Complexes with the Prion Proteins
Theme II: Prion Biology - 12. PrPSC Specific Antibodies: Generation, Structural Analysis, Use as Tools and Diagnostic Assay Development
Theme II: Prion Biology - 13. Discovery and Characterization of Novel Interactions Involving PrP and Related Proteins
Theme II: Prion Biology - 14. Role of the Cellular Prion Protein in Regulating T Cell-Mediated Autoimmune Neuroinflammation
Theme II: Prion Biology - 15. Oligomeric PrPres and Amyloidogenic PrP Fragments: their molecular structure, toxicity, and role in prion disease pathogenesis
Theme II: Prion Biology - 16. PrP, ALS, and Autism Spectrum Disorders
Theme II: Prion Biology - 17. Protein Folding Diseases in Zebrafish
Theme II: Prion Biology - 18. Physiological Functions of the Cellular Prion Protein
Theme II: Prion Biology - 19. Testing potential chemical chaperones for prions with single-molecule spectroscopies
Theme II: Prion Biology - 20. Linking Prion Fibril Stability and Prion Infectivity
Theme III
Theme III: Prion Preparedness and Prevention - Introduction
Theme III: Prion Preparedness and Prevention - 1. The Political Economy of Testing and Traceability Systems in Prion Disease Risk Management
Theme III: Prion Preparedness and Prevention - 2. Developing an Integrated Model of Risk Estimation of BSE and vCJD in
Theme III: Prion Preparedness and Prevention - 3. Risk Analysis and Research Assessment for Iatrogenic Transmission of Variant Creutzfeldt-Jakob Disease (vCJD) During Islet Cell Transplantation Procedures
Theme III: Prion Preparedness and Prevention - 4. In Land and Life: Multi-Scale Implications of Chronic Wasting Disease for
Theme III: Prion Preparedness and Prevention - 5. Characterizing Patterns of Contagion and Transmission of Chronic Wasting
Theme III: Prion Preparedness and Prevention - 6. Expert Elicitation to Improve Risk Estimation for Transmissible Spongiform Encephalopathies for Infectivity in Blood and Other Cells, Tissues and Organs of Humans and Animals
Theme III: Prion Preparedness and Prevention - 7. Prion Diseases and Lab Safety: A Structured Assessment of Prion Risk Perception in Canadian Medical Laboratories




PrP CANADA 2010